Open TCI

Publications

The following publications have acknowledged use of data available on this website:

  1. Masui K, Upton R, Doufas A, Coetzee J, Kazama T, Mortier E, Struys M: The performance of compartmental and physiologically based recirculatory pharmacokinetic models for propofol: a comparison using bolus, continuous, and target-controlled infusion data. Anesth Analg 2010; 111:368–79 PMID: 19861357
  2. Cortínez L, Anderson B, Penna A, Olivares L, Muñoz H, Holford N, Struys M, Sepulveda P: Influence of obesity on propofol pharmacokinetics: derivation of a pharmacokinetic model. Br J Anaesth 2010; 105:448–56 PMID: 20710020
  3. Coetzee J: Allometric or lean body mass scaling of propofol pharmacokinetics: towards simplifying parameter sets for target-controlled infusions. Clin Pharmacokinet 2012; 51:137–45 PMID: 22316280

About Us

The Open TCI Initiative was developed initially by Dr Charles Minto (Sydney, Australia) & Professor Thomas Schnider (St Gallen, Switzerland) based on many discussions over the past years. This opentci.org website was born on 6 January 2008.

The three main goals of the Open TCI Initiative were further developed in discussion with our mentor, Professor Steven L. Shafer, on 17 January 2008 and others at the first meeting in Cape Town on 3 March 2008.

Learn more about us.

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